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So, when Gene Simmons happened to be in town for the 2016 KISS Expo, he dropped by the Visual Japan Summit for a rollicking rendition of a KISS classic.

KISS’s notorious, tongue-wagging bassist joined X Japan and a gaggle of other wildly costumed visual-kei all-stars, including pop-rockers Glay (whose own 1999 Glay Expo gig at Makuhari Messe still holds the Guinness World Record for the largest concert ever held by a single act in Japan) and operatic heavy metal quintet Luna Sea, for a free-for-all singalong of “Rock ‘n’ Roll All Nite” that lived up to its title.

Notably, classical ecologists have set the foundations for the way we analyze these systems, with some techniques dating back to the beginning of the twentieth century.

In this thesis, we expand and where possible reuse these techniques to unravel the hidden patterns comprising the human gut microbiome.

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In Chapter 4, we study IBD from a longitudinal perspective, revealing increased volatility in the gut microbiomes of subjects with IBD, a property that does not appear to be present in unaffected controls.To set an appropriate motivation and context for the rest of this work, Chapter 1 reviews recent discoveries on the human microbiome and how the communities within can influence the effectiveness of therapeutic agents.Next, in Chapter 2, we introduce EMPeror, an interactive analysis and visualization tool that is crucial to the findings presented in later chapters.Earlier that evening, backstage at the Summit, Simmons told Yahoo Music that he hadn’t even rehearsed with X Japan and had no idea what was going to happen.So this group performance was, admittedly, very loose — but it was also the very definition of rock ‘n’ roll.

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